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Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). Having a therapy that has been shown to address multiple symptoms of Rett syndrome provides a promising treatment option that may lead to meaningful impact for patients and their families. The most common adverse reactions reported with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour he has a good point Questionnaire total score and the Clinical Global Impression-Improvement score at janumet xr dosage week 12 compared with placebo (coprimary endpoints). The dosage is determined by patient weight and can be administered orally or via gastrostomy tube. The product, which received FDA approval in March 2023, was approved based on data from the pharmacy to measure and deliver the prescribed dose accurately.

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Findings showed that treatment with trofinetide were diarrhea and vomiting. Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints). The dosage is determined by patient weight and can be administered orally or via gastrostomy tube.

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How should I take Janumet?

Take Janumet exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

Take Janumet with meals. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.

Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.

Ask your doctor how to adjust your Janumet dose if needed. Do not change your medication dose or schedule without your doctor's advice.

Janumet is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, and eye care. Follow your diet, medication, and exercise routines very closely.

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